10 Feb
Dr Reju-All Advanced PDRN Rejuvenating Cream Review – Deep Care
skincare
/ 5 min

Dr Reju-All Advanced PDRN Rejuvenating Cream Review – Deep Care

Dr Reju-All promises pharmaceutical-level skincare with pure ingredients and balance. Is it worth it? What's the results (before-and-after)? Check out our review to find out!

Dr Reju-All has exploded across the beauty scene in South Korea, with a trio of products for deeper, gentle skincare. Known as Korea’s No.1 K-Pharmacy Skincare Brand, they claim to come to skincare with a medical and pharmaceutical background to enhance the effectiveness of skincare ingredients. They see their products as a skin ‘prescription’, designed to achieve a beneficial outcome as a simply designed medication that is transparent and easily applied for the user. Their packaging simply explains the ingredients, when to use and how to add each product to your routine. Their formulas are designed to be simple and even with just three products, they are challenging how other skincare companies are producing products. 

Dr Reju-All Models holding PDRN Advanced Cream in Lab

Although they claim that ‘being viral’ is not their goal – their Advanced PDRN Rejuvenating cream has gone impossibly viral. This tiny, white tube may look quaint and unassuming on sight, but has sold hundreds of thousands of units globally and has a widespread appeal. So, what’s inside the tube? Does a pharmacist-based skincare approach have merit? What are the results of using this single, gentle cream for two weeks? We put it to the test at home to see - is the hype real? 

Dr Reju-All Advanced PDRn Cream in a stack

What's In The Bottle?

Niacinamide: brightening vitamin B3 that helps reduce dark spots and even skin tone for a radiant, smooth finish. Also helps support collagen production for long-term reduction of fine lines. 

  

Hydrolyzed Collagen: deeply moisturizes skin barrier and enhances firming of skin to reduce fine lines and dullness.

   

Sodium Hyaluronate: plumping water humectant that helps draw moisture into the skin barrier and powerfully holds it to maintain lasting hydration and shine.   

 

PDRN (Salmon): DNA fragments that naturally absorb into skin to trigger renewal and cell healing, to produce more youthful and glowing skin. It creates a stronger skin barrier that also cools inflammation and halts cellular aging 

 

Allantoin: revitalizing molecule that enhances exfoliation of dead skin cells, improves regeneration of cells and improves moisture for refreshed skin texture. 

Ivy leaves sitting on soft grey background

Adenosine: moisturizing, anti-aging agent that helps stimulate cell barrier healing, improves peptide and collagen synthesis within cells for brighter and firmer skin.   

 

Neem tree extract: soothing extract that helps reduce acne and inflammation, by reducing redness, irritation and improving collagen production for refreshing previous damage and fine lines. 

 

Panthenol: soothing vitamin B5 that helps strengthen the skin barrier and improve hydration, softness and texture. 
 
Ivy leaf extract: popular in K-Beauty to enhance cell healing, infuse soothing antioxidants and reduce redness

Who Should Avoid?

This light, carefully formulated cream is suitable for all skin types with fine lines. You are likely to see best results with dry skin, inflammation, flaking or fine lines and wrinkles. This cream is least beneficial to oily skin types or could trigger irritation in acne-prone skin where you need softer gel formulas.

Dr Reju-All Advanced PDRN Rejuvenating Cream

The Results

I have sensitive skin with fine lines, that requires soft formulas that don't irritate or dry. This light cream is recommended to be used post-serums and followed by a rich barrier cream, so I started adding it to my daily routine and following it with the Dr Althea 345 Barrier Cream. Dr Reju-All does have their own barrier cream they recommend for this, but I wanted to see the benefits and changes of just the Advanced PDRN cream on its own. 

 

The cream has an incredibly light, soothing texture that is cooling and absorbs quickly. It's quite hydrating on its own, but sealing it in with a stronger barrier cream helped improve skin texture quicker and made my skin feel really soft. I did notice a daily improvement in fine lines (mostly moisture-based).

Skin after using Dr Reju-All Advanced PDRN Cream

In just two weeks, I could see why this product was so popular (especially amongst minimalist skincare lovers). It helped improve fine lines around my eyes, reduce uneven skin textures and created uniform, glowy skin.

 

It provides a gentle, but rich way to improve your skin texture. The main downside is that the tube is small, but lasts about 3 weeks of daily use. It's a really great treatment if you are after a slow-aging treatment that is gentle and soothing (away from more aggressive agents such as retinol, spicules or peeling treatments). It's incredibly suitable for sensitive skin and I would highly recommend it to improve fine lines and uneven skin textures.

Final Thoughts

This rich fine-line reducing cream is one of the most popular in South Korea right now and for such interesting reason. It's minimalist, a step away from concentrated high-intensive treatments, and instead is soothing, nourishing and improves your skin gently over time. If you are after all the benefits of PDRN without any irritation, this is one of the best high-purity PDRN creams in the market.

Explore all the latest releases in K-Beauty on Arktastic! With fresh releases directly shipped from Seoul, we select only the best and brightest. Get excited about skincare with our curated, specialist range.

 

Looking for more skincare reviews? Check out our review of the famous Dr Althea 345 Barrier Cream. Or check out our guide to PDRN:

 

Dr Althea 345 Barrier Cream Review 

The Glowing Benefits of PDRN 

Written by Rahul - Team Arktastic
10 Feb 2026

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